Medical Consequences of Drug Abuse
Drug addiction is a brain disease. Although initial drug use might be
voluntary, drugs of abuse have been shown to alter gene expression and
brain circuitry, which in turn affect human behavior. Once addiction develops,
these brain changes interfere with an individual's ability to make voluntary
decisions, leading to compulsive drug craving, seeking and use.
The impact of addiction can be far reaching. Cardiovascular disease,
stroke, cancer, HIV/AIDS, hepatitis, and lung disease can all be affected
by drug abuse. Some of these effects occur when drugs are used at high
doses or after prolonged use, however, some may occur after just one use.
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